Two couples rent a secluded house for a weekend getaway, and encounter an odd caretaker while facing a dangerous secret.

　　After years on the run, the mystery man known as "Trick" is back, but not on his own terms. Trick finds himself trapped in a cage with four other hostages - all of them paralyzed from the neck down. When Trick realizes that one of the other hostages is an old foe, Detective Epperson, the two begin working together to uncover the connection between them and their captor - a masked man they suspect is the infamous Deathstalker Killer. Meanwhile, Agent Bobby Church of the FBI is investigating Epperson's disappearance and discovers the detective vanished while he had been following a lead in the Deathstalker case. The search soon has Church crossing paths with Epperson's former partner, Scott, himself looking into the abduction of his friend, Olivia. After Scott and Church discover cellphone pictures of Olivia in the cage with both Trick and Epperson, they know they must race against the clock to find the location of the cage before time runs out, and the hostages are executed one-by-one.

　　创意鬼才亨利·塞利克和制片人乔丹·皮尔这次带来动画《恶魔兄弟》，讲述了狡猾的恶魔兄弟温德尔（科甘-迈克尔·凯配音）和瓦尔德（皮尔配音）向凯特·艾略特（一名被负罪感支配的坚强少女）求助，希望她能将他们召唤至人间。但与之相对的，凯特也提出要求，进而引发了一场奇异无比、笑料百出的独特冒险。影片全篇采用定格动画的手工艺术进行制作，是一部无视生死法则的动画狂想曲。